J. Skarżewski

Professor Jacek Skarżewski
Head of Department

Room: 322 / A2
Phone: +48713202464

1972 M.Sc. Chemistry, Wrocław University of Technology
1975     Ph.D. Chemistry, (with Prof. Zofia Skrowaczewska), Wrocław University of Technology
1987   Habilitation
2001   Full Professor

Fellowships:
1976-1978  Postdoc, Gunma University, Kiryu, Japan
1984 Research visit, Universitat der Stuttgart, Germany

Current research interests:
The main effort is in the area of organic synthesis with particular concern of application of new catalytic reactions and reagents.  Currently conducted research including graduate and undergraduate projects is aimed at synthesis and application of chiral ligands in transition metal-catalyzed enantioselecive transformations.  Additional branch deals with the synthesis of alkaloid derivatives and their organocatalytic applications.

Recent papers
1. Stereochemistry of Phosphonylation of 9-Aminoquinine Schiff Bases, P. J. Boratyński, J. Skarżewski, Ł. Sidorowicz Arkivoc, 2012, 204-215.
2. Easy Access to 9-Epimers of Cinchona Alkaloids: One-pot Inversion by Mitsunobu Esterification – Saponification, Ł. Sidorowicz, J. Skarżewski, Synthesis, 2011, 708-710.
3. Enantioselective Henry reaction catalyzed by copper(II) – Cinchona alkaloid complexes M. Zielińska-Błajet, J. Skarżewski, Tetrahedron: Asymmetry 2011, 22, 351-355.
4. Photo-induced structural changes in two crystal forms with different numbers of independent molecules, J. Bąkowicz, J. Skarżewski, I. Turowska-Tyrk, Cryst. Eng. Comm. 2011, 13, 4332-4338.
5. Enantiopure trans 1-amino-2-(arylsulphanyl)cyclohexanes: Novel chiral motif for chiral ligands and orgaoncatalysts, A. E. Nowak, E. Wojaczyńska, J. Skarżewski, Tetrahedron: Asymmetry 2011, 22, 1687–1691.
6. Sulfoxides derived from Cinchona alkaloids – chiral ligands in palladium-catalyzed asymmetric allylic alkylation, E. Wojaczyńska , M. Zielińska-Błajt, I. Turowska-Tyrk, J. Skarżewski, Tetrahedron: Asymmetry 2010, 21, 853-858.
7. New functional derivatives of 9-phenyl-quinine, P. J. Boratyński, J. Skarżewski Synthesis, 2009, 3113-3119.
8. Asymmetric nitroaldol reaction catalyzed by copper-diamine complexes:  Selective construction of two contiguous stereogenic centers, R. Kowalczyk, J. Skarżewski, Tetrahedron: Asymmetry 2009, 20, 2467–2473.
9. New Chiral Thiols and C2-Symmetrical Disulfides of Cinchona Alkaloids: Ligands for Asymmetric Henry Reaction Catalyzed by CuII Complexes, M. Zielińska-Błajet, J. Skarżewski, Tetrahedron: Asymmetry 2009, 20, 1992–1998.
10. Enantioselective Nitroaldol Reaction Catalyzed by Sterically Modified Salen-Chromium Complexes R. Kowalczyk, P. Kwiatkowski, J. Skarżewski, J. Jurczak J. Org. Chem. 2009, 74, 753–756.
11. An effective deracemisation of 1,2-bis(phenylsulfanyl)cyclohexane, E. Wojaczyńska, J. Skarżewski, Phosphorus, Sulfur, and Silicon 2009, 184, 1323-1331.
12. Asymmetric Henry reaction catalyzed by chiral secondary diamine-copper (II) complexes, R. Kowalczyk, Ł. Sidorowicz, J. Skarżewski, Tetrahedron: Asymmetry 2008, 19, 2310–2315.
13. Chelating 2-azanorbornyl derivatives as effective nitrogen-nitrogen and nitrogen-chalcogen donating ligands in palladium-catalyzed asymmetric allylic alkylation,                E. Wojaczyńska, J. Skarżewski, Tetrahedron: Asymmetry 2008, 19, 2252-2257.
14. Stereoselective C9 Carbon−Carbon Couplings of Quinine: Synthesis and Conformational Analysis of New C2-Symmetric Dimers, P. J. Boratyński, I. Turowska-Tyrk, J. Skarżewski J. Org. Chem. 2008, 73, 7357-7360.
15. Novel C2-symmetric chiral ligands: Enantioselective transformation of cyclic 1,2-diols into 1,2-bis(phenylsulfenyl) and 1,2-bis(phenylselenyl) derivative, E. Wojaczyńska, J. Skarżewski, Tetrahedron: Asymmetry 2008, 19, 593–597
16. Stereoselective C9 Arylation and Vinylation of Cinchona Alkaloids P. J. Boratyński, I. Turowska-Tyrk, J. Skarżewski, Org. Lett. 2008, 10, 385-388.
17. Selective nucleophilic substitution using pyrazolate anions: Easy approach to modular chiral ligands with complexing pyrazole moieties, R. Kowalczyk, J. Skarżewski, Polish J. Chem., 81, 1981-1999 (2007).
18. Asymmetric nitroaldol reaction catalyzed by a chromium(III)-salen system, R. Kowalczyk, Ł. Sidorowicz, J. Skarżewski, Tetrahedron: Asymmetry 2007, 18, 2581-2586.
19. Chiral phenylselenyl derivatives of pyrrolidine and Cinchona alkaloids: nitrogen-seleniun donating ligands in palladium-catalyzed asymmetric allylic alkylation, M. Zielińska-Błajet, R. Siedlecka, J. Skarżewski, Tetrahedron: Asymmetry 2007, 18, 131-136.

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